Pfizer
Sr. Manager, Site Reliability/Operations Engineering Lead, R&D DP&TS Platform and Data Engineering
Be an Early Applicant
The Site Reliability/Operations Engineering Lead will ensure the reliability of cloud-native platforms, manage infrastructure, automate tasks, and lead a high-performing team while collaborating on CI/CD and ensuring security compliance.
ROLE SUMMARY
Pfizer's mission to deliver breakthroughs that change patients' lives is rooted in our commitment to science and innovation. Within Discovery, Preclinical, and Translational Solutions (DP&TS), we accelerate the journey from target identification to clinical translation by leveraging advanced digital technologies, AI, and data-driven insights.
We're building a forward-thinking platform engineering team dedicated to delivering secure, scalable, and resilient infrastructure. As a Site Reliability/Operations Engineering Lead, you'll play a pivotal role in ensuring the reliability, performance, and operational excellence of our cloud-native platforms.
This role is perfect for a high-caliber, well-rounded generalist who thrives in dynamic environments, takes initiative, and enjoys solving complex problems across infrastructure, automation, and observability. You'll be joining a team that values curiosity, collaboration, and continuous learning. While we expect you to take ownership and solve meaningful problems, you'll be supported by a friendly, inclusive environment with clear goals, strong mentorship, and a culture of shared success. We believe in setting our team up to thrive-not just deliver.
ROLE RESPONSIBILITIES
Each day brings a mix of routine and challenge. You'll start by reviewing system health and platform metrics, ensuring everything is running smoothly. From there, you'll collaborate with teammates to prioritize work-whether it's deploying infrastructure, refining automation, or addressing a new technical challenge. Some days you'll be deep in Terraform modules or Kubernetes tuning; other days you'll be troubleshooting unexpected issues or helping a colleague solve a complex problem. You'll have space for focused work, but also plenty of opportunities to engage with others, share ideas, and contribute to solutions that drive real value. The environment is fast-paced but supportive, and your contributions will directly impact the reliability, scalability, and security of the platform.
Key Responsibilities
BASIC QUALIFICATIONS
PREFERRED QUALIFICATIONS
Work Location Assignment: On Premise
The annual base salary for this position ranges from $120,800.00 to $201,400.00.* In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
* The annual base salary for this position in Tampa, FL ranges from $108,700.00 to $181,100.00.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Information & Business Tech
Pfizer's mission to deliver breakthroughs that change patients' lives is rooted in our commitment to science and innovation. Within Discovery, Preclinical, and Translational Solutions (DP&TS), we accelerate the journey from target identification to clinical translation by leveraging advanced digital technologies, AI, and data-driven insights.
We're building a forward-thinking platform engineering team dedicated to delivering secure, scalable, and resilient infrastructure. As a Site Reliability/Operations Engineering Lead, you'll play a pivotal role in ensuring the reliability, performance, and operational excellence of our cloud-native platforms.
This role is perfect for a high-caliber, well-rounded generalist who thrives in dynamic environments, takes initiative, and enjoys solving complex problems across infrastructure, automation, and observability. You'll be joining a team that values curiosity, collaboration, and continuous learning. While we expect you to take ownership and solve meaningful problems, you'll be supported by a friendly, inclusive environment with clear goals, strong mentorship, and a culture of shared success. We believe in setting our team up to thrive-not just deliver.
ROLE RESPONSIBILITIES
Each day brings a mix of routine and challenge. You'll start by reviewing system health and platform metrics, ensuring everything is running smoothly. From there, you'll collaborate with teammates to prioritize work-whether it's deploying infrastructure, refining automation, or addressing a new technical challenge. Some days you'll be deep in Terraform modules or Kubernetes tuning; other days you'll be troubleshooting unexpected issues or helping a colleague solve a complex problem. You'll have space for focused work, but also plenty of opportunities to engage with others, share ideas, and contribute to solutions that drive real value. The environment is fast-paced but supportive, and your contributions will directly impact the reliability, scalability, and security of the platform.
Key Responsibilities
- Ensure high availability and performance of cloud infrastructure and services (AWS, Azure)
- Build and maintain monitoring, alerting, and observability systems (e.g., Prometheus, Grafana, ELK)
- Automate operational tasks using Terraform, Ansible, and scripting languages
- Manage incident response, root cause analysis, and postmortems
- Collaborate on CI/CD pipelines and deployment strategies using **GitHub Actions**
- Maintain and improve container orchestration platforms (Kubernetes, Docker)
- Administer systems, databases, and networks with a focus on reliability and security
- Implement and enforce security and compliance best practices
- Continuously evaluate and integrate tools to improve operational efficiency
- Lead and grow a high-performing team of reliability and operations engineers
BASIC QUALIFICATIONS
- Education: Bachelor's degree in a relevant field (e.g., Computer Science, Data Science, Bioinformatics, Engineering, or related discipline)
- 6+ years of experience in site reliability, operations, or infrastructure engineering
- Strong experience with AWS or Azure
- Proficiency in Terraform, Ansible, and GitHub
- Solid understanding of Kubernetes, Docker, and container orchestration
- Strong scripting skills (e.g., Bash, Python, Typescript)
- Experience with Linux/Unix system administration
- Familiarity with networking, security, and database administration
- Proven troubleshooting and incident management skills
- Fluent in English; capable of clear technical communication across scientific and engineering disciplines
- Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
PREFERRED QUALIFICATIONS
- Experience with observability and logging tools (e.g., OpenTelemetry, Prometheus, Grafana, ELK)
- Knowledge of secrets management (e.g., HashiCorp Vault, AWS Secrets Manager)
- Experience working in regulated environments or with compliance frameworks (e.g., GxP, SOC2, HIPAA)
Work Location Assignment: On Premise
The annual base salary for this position ranges from $120,800.00 to $201,400.00.* In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
* The annual base salary for this position in Tampa, FL ranges from $108,700.00 to $181,100.00.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Information & Business Tech
Top Skills
Ansible
AWS
Azure
Bash
Docker
Elk
Git
Grafana
Kubernetes
Prometheus
Python
Terraform
Typescript
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